Research Grants Awarded

Reseach grants support Minnesota scientific and medical research that has the potential to translate to clinical advances in regenerative medicine. Grants typically open every September. Learn more about how to apply for a grant by reading our frequently asked questions. 

 

View research grants awarded by year.
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Robert Tranquillo, PhD
Rapidly Endothelialized Vascular Bypass Grafts From Autologous Adipose Microvessels
The project aims to develop and test a novel method to create replacement blood vessels that are rapidly seeded with cells derived from a simple…
2022-2024
Juan Carlos Rivera-Mulia, PhD
Juan Carlos Rivera-Mulia, PhD
A multi-omics approach for the identification of species-specific developmental states and speed during interspecies chimerism
1. Construct integrative models that characterize the developmental states and rhythms of early embryogenesis. 2. Identify the developmental…
2022-2024
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Rory Smoot, MD
Augmenting Liver Regeneration at the Single Cell Level
This application examines the mechanisms by which targeting the molecule YAP with medications can facilitate liver regeneration. We propose that YAP…
2022-2024
Joseph Metzger, PhD
Joseph Metzger, PhD
Advancing a genetically edited biosensor platform in human induced pluripotent stem cell-derived cardiac muscle for personalized medicine and drug discovery
This proposal focuses on leveraging advances in cardiac stem cell biology to forge new therapeutic modalities for combating heart disease, the…
2022-2024
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Qiuying Liu, PhD
Mechanistic studies on a congenital hydrocephalus causing mutation in Trim71
Congenital hydrocephalus is a major cause of childhood morbidity. Mutations in Trim71, a conserved stem-cell-specific RNA-binding protein, cause this…
2022-2024
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James Dutton, PhD
Pre-clinical evaluation of drug treatments to prevent vision loss from Dry Age-Related Macular Degeneration using patient-derived iPSC-RPE
Dry Age related macular degeneration is a chronic disease of aging that causes progressive loss of vision due to damage to the RPE cell layer in the…
2022-2024
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Aaron Krych, MD
MSC facilitated cartilage recycling for hip defects
The overall goal of this study is to test the safety and feasibility for a one-stage cartilage restoration procedure for symptomatic defects of the…
2022-2024
Dr. Siegler
Elizabeth Siegler, PhD
Bioengineering of Mesenchymal Stromal Cells for Regenerative Medicine
Mesenchymal stromal cells (MSCs) have intrinsic immunosuppressive and regenerative properties. We seek to engineer MSCs with artificial receptors to…
2021-2023
Dr. Kostallari
Enis Kostallari, PhD
Epigenetic inhibition of inflammation in alcoholic hepatitis
Public Health Relevance: Alcoholic Hepatitis (AH) is a severe liver disease and is a leading cause of morbidity and mortality in the United States of…
2021-2023
Dr. Abdel
Matthew Abdel, MD
First-in-class pharmacotherapies for arthrofibrosis
Joint stiffening (arthrofibrosis) is a debilitating complication with limited treatment options that is observed in a substantial subset of patients…
2021-2023
Dr. Scarisbrick
Isobel Scarisbrick, PhD
Pharmacoregeneration for Chronic Spinal Cord Injury
Our goal is to develop a new treatment strategy that improves outcomes in individuals with chronic spinal cord injury. Studies will contribute to the…
2021-2023
Dr. Ogle
Brenda Ogle, PhD
A humanized model of hypertrophic cardiomyopathy (HCM) to study disease onset and progression in response to volumetric pressure loads
The clinical prognosis for patients with hypertrophic cardiomyopathy (HCM) is very poor and the only long-term alternative is heart transplant. Our…
2021-2023