Discovery Knows No Bounds

Discovery knows no bounds

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Human hematopoiesis in genetically modified swine

Biobusiness Grant Recipient: Ohad Gafni, PhD

Grant Period: 2019-2020

Award Value: $100,000

Site: Recombinetics Inc.

Project Summary: Our goal is to engineer a humanized swine model that carries key human cytokines, this strategy will provide the immunology field a high capacity and robust platform that promotes hematopoietic stem cells, CAR T cells, innate immune cells production, differentiated and cultured in high volume bioincubators. Humanized MISTRG porcine model could also become the new gold standard of immune response therapies before the final step of stage four of drug testing for human applications, altering the mouse as the commonly used model.

Ohad Gafni, PhD