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Girk channels in cartilage development and repair

Research Grant Recipient: Jennifer Westendorf, PhD

Award Value: $250,000

Research Focus: Osteoarthritis

Project Summary: This project will help determine how proteins called Girk2 and Girk3 contribute to cartilage formation and repair in the setting of osteoarthritis. The investigators believe that osteoarthritis can be prevented if these proteins are absent or inactive. This work will lead to the development of better strategies to treat osteoarthritis.

Dr. Westendorf studies the molecular the epigenetic basis for skeltal formation, the regeneration of bone and cartilage, and the growth of pirmary and metastatic bone tumors. She is the vice chair of the Department of Biochemistry and Molecular Biology, and a consultant for the Department of Orthopedic Surgery at Mayo Clinic.

Jennifer Westendorf, PhD