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Development of inducible immunodeficient swine

Biobusiness Grant Recipient: Dan Carlson, PhD

Grant Period: 2017-2018

Award Value: $100,000

Site: Recombinetics

Project Summary:

Immunodeficient swine have tremendous potential in basic and pre-clinical research; however, difficulties in propagation have impeded commercial availability.  As a solution, we propose to build and test a conditional rescue cassette to pair with our RAG2/IL2Rg knockout swine to enable propagation.  If successful, this project will lead to the first commercially available immunodeficient pig for regenerative medicine research and development.

Read Carlson’s final report here

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