Activating the Hippo pathway effector YAP to augment liver regeneration
Research Grant Recipient: Rory Smoot, MD
Award Value: $250,000
Research Focus: regenerating the liver
From the investigator:
The goal of this proposal is to speed up liver regeneration by activation a regeneration pathway with a drug treatment. This will be tested in multiple models, including models in which regeneration is not as good at baseline. Positive results would provide a potential treatment to improve liver function in patients suffering from liver failure.