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Activating the Hippo pathway effector YAP to augment liver regeneration

Research Grant Recipient: Rory Smoot, MD

Award Value: $250,000

Research Focus: regenerating the liver

From the investigator:

The goal of this proposal is to speed up liver regeneration by activation a regeneration pathway with a drug treatment. This will be tested in multiple models, including models in which regeneration is not as good at baseline. Positive results would provide a potential treatment to improve liver function in patients suffering from liver failure.

Rory Smoot, MD