CELLTOP: A Phase I Clinical Trial of Autologous Adipose Derived Mesenchymal Stem Cells in the Treatment of Paralysis due to Traumatic Spinal Cord Injury
Research Grant Recipient: Mohamed Bydon, MD
Award Value: $500,000
Research Focus: Spinal cord injury
Project Summary: This clinical trial investigates whether adipose-derived (fat tissue-derived) mesenchymal stem cells can be safely administered into the cerebrospinal fluid of patients with traumatic spinal cord injury and what the effects this may have on functional improvement, activities of daily living, and quality of life. If successful, this study may create a viable clinical option for spinal cord injury patients by establishing feasibility and safety data for patients who do not have many treatment options.
Dr. Bydon is a neurosurgeon who is fellowship-trained in complex spinal surgery and spinal oncology. He is a principal investigator of the Mayo Clinic Neuro-Informatics Laboratory and the medical director of the Mayo Clinic Neurosurgical Registry, a database focused on improving outcomes and safety for patients.